Sildenafil Citrate Sildenafil Citrate: Side Effects Uses Dosage Interactions Warnings: Revision history

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27 November 2025

  • curprev 12:5112:51, 27 November 2025SQQTerrell talk contribs 5,119 bytes +5,119 Created page with "<br><br><br>Sildenafil citrate is exonerated predominantly by the CYP3A4 (John Major route) and CYP2C9 (minor route) hepatic microsomal isoenzymes. The Major circulating metabolite results from Ndesmethylation of sildenafil, and is itself advance metabolized. This metabolite has a PDE selectivity profile alike to sildenafil and an in vitro potentiality for PDE5 approximately 50% of the parent do drugs.<br>In that respect are no restricted clinical data on the refuge oref..."